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In this study, the benefits of nolvadex appeared to be independent of estrogen receptor status.

Women taking nolvadex to reduce the incidence of breast cancer should have a breast examination, a mammogram, and a gynecologic examination prior to the initiation of therapy.

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Other side effects of nolvadex include vomiting, nausea, numbness in the body, excessive sweating and hot flashes.

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Doses given in these patients were all greater than 400 mg m 2 loading dose, followed by maintenance doses of 150 mg m 2 of nolvadex given twice a day.

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