Patients with serious psychiatric illness such as schizophrenia, bipolar disorder, and major depressive disorder did not participate in the pre-marketing studies of zyban.
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Additionally, the following psychiatric adverse events were reported in 2 of patients in either treatment group zyban vs.
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Patients should be made aware that wellbutrin contains the same active ingredient found in zyban, used as an aid to smoking cessation treatment, and that wellbutrin should not be used in combination with zyban, or any other medications that contain bupropion, such as wellbutrin sr bupropion hydrochloride , the sustained-release formulation or wellbutrin xl bupropion hydrochloride , the extended-release formulation.
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Wellbutrin, wellbutrin sr, and wellbutrin xl are not approved for smoking cessation treatment, but bupropion under the name zyban is approved for this use.
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